The Messenger of Allah (ﷺ) prohibited unclean medicine.
Sunan Abi Dawud Book 29, Hadith 16
← Previous Hadith I heard the Messenger of Allah (ﷺ) say: If I drink an antidote, or tie an amulet, or compose poetry, I am the type who does not care what he does.

Abu Dawud said: THis was peculiar to the Prophet (ﷺ), but some people have allowed to use it, i.e. antidote.

Sunan Abi Dawud Book 29, Hadith 15 Next Hadith → When a physician consulted the Prophet (ﷺ) about putting frogs in medicine, he forbade him to kill them.

Sunan Abi Dawud Book 29, Hadith 17